Medical Research Platform (MRP) is proud to present a groundbreaking study titled “Causes of Death After Laryngeal Cancer Diagnosis: A US Population-Based Study.” This comprehensive research, authored by Mohammed Ahmed Sadeq and Mohamed Elsaid, sheds light on the common causes of death following a diagnosis of laryngeal cancer (LC) in the United States. The study aims to provide valuable insights into the prognosis and non-cancer-related mortality rates among LC patients. The findings of this study have been published in the prestigious journal, European Archives of Oto-Rhino-Laryngology.
Members
Mohammed Ahmed Sadeq
Mohamed Elsaid
ResearchGate link
Causes of death after laryngeal cancer diagnosis: A US population-based study
Journal
European Archives of Oto-Rhino-Laryngology
Background
While several studies have examined the survival rates of patients with laryngeal cancer, most of them have focused solely on the prognosis of the disease. Only a limited number of studies have explored the causes of death unrelated to cancer in this population. Therefore, the objective of this study was to investigate and quantify the most common causes of death following a diagnosis of laryngeal cancer.
Methods
The study utilized data from the Surveillance, Epidemiology, and End Results (SEER) program, which included information on 44,028 patients diagnosed with laryngeal cancer in the United States between 2000 and 2018. The researchers analyzed the data and stratified the patients based on various demographic and clinical parameters. Standardized mortality ratios (SMRs) were calculated to determine the risk of death from different causes.
Key Findings
During the follow-up period, a total of 25,407 deaths were reported among the laryngeal cancer patients, accounting for 57.7% of the study population. The highest number of fatalities (11,121; 43.8%) occurred within 1 to 5 years following the diagnosis of laryngeal cancer. Interestingly, non-cancer causes of death were found to be the leading cause, accounting for 35.2% (8,945) of the deaths. Deaths directly attributed to laryngeal cancer accounted for 34.3% (8,705), while deaths from other cancers accounted for 30.5% (7,757).
Common Non-Cancer Causes of Death
Among the non-cancer causes of death, heart diseases were the most prevalent, accounting for 4.42 times the expected number of deaths compared to the general population. Other significant non-cancer causes of death included chronic obstructive pulmonary diseases (COPD) with a standardized mortality ratio (SMR) of 4.90, cerebrovascular diseases with an SMR of 4.28, and other non-cancer causes with an SMR of 3.93.
Implications and Conclusions
The study’s findings highlight an important revelation: non-cancer causes of death surpass deaths directly attributed to laryngeal cancer itself among LC patients. This insight has significant implications for counseling and guiding laryngeal cancer survivors regarding their future health risks. It emphasizes the importance of addressing and managing non-cancer-related health conditions, particularly heart diseases, COPD, and cerebrovascular diseases, in this population.
Contribution to Medical Research
The publication of this study in the European Archives of Oto-Rhino-Laryngology signifies MRP’s commitment to advancing medical knowledge and understanding. By shedding light on the causes of death after laryngeal cancer diagnosis, this research adds to the growing body of literature surrounding LC and its impact on patient outcomes. MRP extends its gratitude to the study authors, Mohammed Ahmed Sadeq and Mohamed Elsaid, for their dedication and expertise in conducting this study.
Join Us in Making a Difference
At Medical Research Platform (MRP), we invite researchers, medical professionals, and individuals passionate about making a difference to join our vibrant community. By becoming a part of MRP, you will have the opportunity to collaborate with esteemed researchers like Mohammed Ahmed Sadeq and Mohamed Elsaid, access cutting-edge resources, and contribute to groundbreaking studies that shape the future of medical science. Together, let’s push the boundaries of knowledge and create a brighter, healthier future for all.
Conclusion
The publication of this research article in the European Archives of Oto-Rhino-Laryngology marks a significant milestone for Medical Research Platform (MRP). We remain committed to excellence, innovation, and the pursuit of knowledge in the field of medical research. We extend our gratitude to the dedicated authors, Mohammed Ahmed Sadeq and Mohamed Elsaid, and invite others to join us on this remarkable journey. Together, let’s continue to unlock new frontiers in medical research and make a lasting impact on global healthcare.
Stay tuned for more updates and groundbreaking research from MRP as we strive to make a difference in the world of medical science.